Trimethoprim, Creatinine and Creatinine-Based Equations
نویسندگان
چکیده
منابع مشابه
Trimethoprim, creatinine and creatinine-based equations.
Co-trimoxazole is a frequently prescribed antibiotic worldwide. It is composed of both trimethoprim and sulfamethoxazol (Sfx) and is used in the treatment and prophylaxis of urinary tract and Pneumocystis jirovecii infections. The Sfx component appears to be nephrotoxic at high doses or doses inappropriately adjusted for glomerular filtration rate (GFR). The trimethoprim component, even at reco...
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The effects of a 10-day course of moderate-dose (10 mg/kg/day) or high-dose (20 mg/kg/day) trimethoprim therapy on serum creatinine, measured creatinine clearance, urinary creatinine excretion, and serum folate were studied in 20 healthy volunteers. Serum creatinine concentrations increased significantly during trimethoprim therapy, began to decrease near day 10, and returned to baseline during...
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ژورنال
عنوان ژورنال: Nephron Clinical Practice
سال: 2011
ISSN: 1660-2110,1660-2110
DOI: 10.1159/000328911